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Osisko Metals Incorporated (the ‘ Company or ‘ Osisko Metals ‘) ( TSX-V: OM ; OTCQX: OMZNF ; FRANKFURT: 0B51 ) is pleased to announce new drill results from the Gaspé Copper Project, located in the Gaspé Peninsula of Eastern Québec.

Osisko Metals Chief Executive Officer Robert Wares commented: ‘ Drill results at Gaspé Copper continue to exceed expectations. These new data expand the deposit further south and at depth with drill holes 30-1092 and 30-872, located respectively 230 metres and 440 metres south of the 2024 Mineral Resource Estimate (‘MRE’) model. Additional holes are planned in this resource expansion target area in the coming months over a surface of 450 metres by 550 metres, which we believe will add significant new tonnage to the MRE update, planned for Q1 2026.

New analytical results are presented below (see Table 1), including 20 mineralized intercepts from 7 new drill holes. Infill intercepts are located inside the 2024 MRE model ( see November 14, 2024 news release ), and are focused on upgrading inferred mineral resources to measured or indicated categories, as applicable. Expansion intercepts are located outside the 2024 MRE model and may potentially lead to additional resources that will be classified appropriately within the next MRE update. Some of the reported intercepts have contiguous shallower infill as well as deeper expansion (noted on Table 1 below as ‘Both**’). Maps showing hole locations are available at www.osiskometals.com .

Highlights:

  • Drill hole 30-1096
    • 730.7 metres averaging 0.29% Cu (infill and expansion)
  • Drill hole 30-1085
    • 219.0 metres averaging 0.41% Cu (infill)
    • 754.5 metres averaging 0.24% Cu (infill and expansion)
  • Drill hole 30-1092
    • 331.5 metres averaging 0.37% Cu (expansion)
  • Drill hole 30-1095
    • 309.5 metres averaging 0.26% Cu (infill)
  • Drill hole 30-1098
    • 115.0 metres averaging 0.29% Cu (infill)
    • 124.5 metres averaging 0.20% Cu (expansion)
  • Drill hole 30-1099
    • 614.7 metres averaging 0.23% Cu (infill and expansion)
  • Drill hole 30-0872
    • 92.1 metres averaging 0.24% Cu (expansion)
    • 47.2 metres averaging 1.14% Cu (expansion)

Table 1: Infill and Expansion Drilling Results

DDH No. From (m) To (m) Length (m) Cu % Ag g/t Mo % CuEq* Type**
30-0872 167.6 259.7 92.1 0.24 3.05 0.25 Expansion
And 342.0 389.2 47.2 1.14 11.84 1.22 Expansion
30-1085 3.0 222.0 219.0 0.41 2.79 0.44 Infill
And 355.5 1110 754.5 0.24 1.63 0.019 0.32 Both
(including) 355.5 763.3 407.8 0.21 1.49 0.020 0.30 Infill
(including) 763.3 1110.0 346.7 0.27 1.79 0.019 0.36 Expansion
30-1092 15.0 346.5 331.5 0.37 3.21 0.39 Expansion
30-1095 15.0 43.0 28.0 0.22 1.75 0.23 Infill
And 57.0 366.5 309.5 0.26 2.11 0.007 0.30 Infill
And 425.9 482.0 56.1 0.23 1.70 0.24 Expansion
And 524.7 550.5 21.9 0.42 2.04 0.43 Expansion
30-1096 27.0 78.0 51.0 0.21 1.40 0.22 Infill
And 129.0 177.0 48.0 0.17 1.20 0.18 Infill
And 331.5 1062.2 730.7 0.29 1.60 0.032 0.42 Both
(including) 331.5 727.5 396.0 0.21 1.45 0.032 0.34 Infill
(including) 727.5 1062.2 334.7 0.39 1.79 0.032 0.52 Expansion
30-1098 36.0 141.0 104.5 0.20 2.25 0.21 Infill
And 255.0 288.0 33.0 0.21 1.18 0.22 Infill
And 330.0 445.5 115.0 0.29 2.18 0.017 0.36 Infill
And 606.0 730.5 124.5 0.20 1.57 0.014 0.26 Expansion
And 753.0 813.0 60.0 0.35 2.88 0.006 0.39 Expansion
30-1099 31.5 66.0 34.5 0.22 1.08 0.23 Infill
And 105.3 720.0 614.7 0.23 1.59 0.016 0.30 Both
(including) 105.3 578.0 472.7 0.23 1.61 0.017 0.30 Infill
(including) 578.0 720.0 142.0 0.23 1.52 0.015 0.30 Expansion
And 862.2 1000.5 138.0 0.13 1.01 0.028 0.24 Expansion

* See explanatory notes below on copper equivalent values and Quality Assurance / Quality Control.
** ‘Both’ indicates drill holes that have contiguous shallower infill as well as deeper expansion intercepts.

Discussion

Drill hole 30-0872 was an old Noranda hole from the 1990s from which core was recovered and analyzed. The hole is located 440 metres south of the southern limit of 2024 MRE model and returned 92.1 metres averaging 0.24% Cu and 3.05 g/t Ag followed by a higher grade second intercept of 47.2 metres averaging 1.14% Cu and 11.8 g/t Ag (at the level of the C Zone skarn horizon), extending mineralization to a vertical depth of 390 metres. The first intercept starts at a depth of 168 metres and the overlying stratigraphy (Indian Cove hornfels) is unmineralized, but this waste material may be included as necessary strip in the next Whittle pit shell.

Drill hole 30-1085, located on top of Copper Mountain near the central part of the 2024 MRE model, intersected 219.0 metres averaging 0.41% Cu and 2.79 g/t Ag (infill), followed by a second intercept (starting 130 metres deeper) of 754.5 metres averaging 0.24% Cu, 1.63 g/t Ag and 0.019% Mo (both infill and expansion at depth).This hole extends mineralization near the centre of the deposit to a vertical depth of 1110 metres.

Drill hole 30-1092 is located 230 metres south of the southern limit of 2024 MRE model and returned 331.5 metres averaging 0.37% Cu and 3.21 g/t Ag (from surface down to the P4 stratigraphic level below the C Zone). This hole is located approximately 15 metres west of previously-reported hole 30-1067, which had failed to drill through a pillar of the B Zone.

Drill hole 30-1095, located in the south-central part of the 2024 MRE model, intersected 309.5 metres averaging 0.26% Cu and 2.11 g/t Ag (infill). This was followed by 56.1 metres averaging 0.23% Cu and 1.70 g/t Ag and then by another 21.9 metres averaging 0.42% Cu and 2.04 g/t Ag (both expansion), extending mineralization to a vertical depth of 550 metres.

Drill hole 30-1096, located in the central part of the 2024 MRE model, intersected two short (51 and 48 metre-long) mineralized zones, followed by 730.7 metres averaging 0.29% Cu, 1.60 g/t Ag, and 0.032% Mo (0.42% CuEq). The latter includes an expansion lower intercept, below the base of the 2024 MRE model, of 334.7 metres averaging 0.39% Cu, 1.79 g/t Ag, and 0.032% Mo (0.52% CuEq). This hole extends mineralization to a vertical depth of 1062 metres.

Drill hole 30-1098, located near the western margin of the 2024 MRE model, intersected 104.5 metres averaging 0.20% Cu and 2.25 g/t Ag (infill), followed by 115.0 metres averaging 0.29% Cu and 2.18 g/t Ag (infill). This was followed by 124.0 metres averaging 0.20% Cu and 1.57 g/t Ag and then by another 60.0 metres averaging 0.35% Cu and 2.88 g/t Ag (both expansion), extending mineralization to a vertical depth of 813 metres.

Drill hole 30-1099, located near the central part of the 2024 MRE model, adjacent to the Copper Mountain pit, intersected a short (34-metre-long) mineralized zone followed by 614.7 metres averaging 0.23% Cu, 1.59 g/t Ag, and 0.016% Mo (both infill and expansion), followed by a third intersection of 138 metres that averaged 0.13% Cu, 1.01 g/t Ag, and 0.028% Mo (expansion), extending mineralization in the porphyry core of the deposit to a vertical depth of 1000 metres.

Mineralization at Gaspé Copper is of porphyry copper/skarn type and occurs as disseminations and stockworks of chalcopyrite with pyrite or pyrrhotite and minor bornite and molybdenite. At least five retrograde vein/stockwork mineralizing events have been recognized at Copper Mountain, which overprint earlier prograde skarn and porcellanite-hosted mineralization throughout the Gaspé Copper system. Porcellanite is a historical mining term used to describe bleached, pale green to white potassic-altered hornfels. Subvertical stockwork mineralization dominates at Copper Mountain whereas prograde bedding-replacement mineralization, that is mostly stratigraphically controlled, dominates in the area of Needle Mountain, Needle East, and Copper Brook. High molybdenum grades (up to 0.5% Mo) were locally obtained in both the C Zone and E Zone skarns away from Copper Mountain.

The 2022 to 2024 Osisko Metals drill programs were focused on defining open-pit resources within the Copper Mountain stockwork mineralization ( see May 6, 2024 MRE press release ). Extending the resource model south of Copper Mountain into the poorly-drilled prograde skarn/porcellanite portion of the system subsequently led to a significantly increased resource, mostly in the Inferred category ( see November 14, 2024 MRE press release ).

The current drill program is designed to convert the November 2024 MRE to Measured and Indicated categories, as well as test the expansion of the system deeper into the stratigraphy and laterally to the south and southwest towards Needle East and Needle Mountain respectively. The November 2024 MRE was limited at depth to the base of the L1 skarn horizon (C Zone), and all mineralized intersections below this horizon represent potential depth extensions to the deposit, to be included in the next scheduled MRE update in Q1 2026.

All holes are being drilled sub-vertically into the altered calcareous stratigraphy which dips 20 to 25 degrees to the north. The L1 (C Zone) the L2 (E Zone) skarn/marble horizons were intersected in most holes, as well as intervening porcellanites that host the bulk of the disseminated copper mineralization.

Table 2: Drill hole locations

DDH No. Azimuth (°) Dip (°) Length (m) UTM E UTM N Elevation
30-0872 0.00 -90.00 594.3 316531.1 5425181.2 706.3
30-1085 0.00 -90.00 1110.0 316020.0 5426400.0 742.5
30-1092 0.00 -90.00 741.0 316342.0 5425425.0 609.0
30-1095 0.00 -90.00 696.0 316409.1 5425733.0 572.8
30-1096 0.00 -90.00 1069.0 316198.0 5426305.0 753.3
30-1098 0.00 -90.00 861.0 316034.0 5425948.0 600.5
30-1099 0.00 -90.00 1041.0 315700.0 5426462.0 603.7

Explanatory note regarding copper-equivalent grades

Copper Equivalent grades are expressed for purposes of simplicity and are calculated taking into account: 1) metal grades; 2) estimated long-term prices of metals: US$4.25/lb copper, $20.00/lb molybdenum and US$24/oz silver; 3) estimated recoveries of 92%, 70% and 70% for Cu, Mo and Ag respectively; and 4) net smelter return value of metals as percentage of the price, estimated at 86.5%, 90.7% and 75.0% for Cu, Mo and Ag respectively.

Qualified Person

The scientific and technical content of this news release has been reviewed and approved by Mr. Bernard-Olivier Martel, P. Geo. (OGQ 492), an independent ‘qualified person’ as defined by National Instrument 43-101 – Standards of Disclosure for Mineral Projects (‘NI 43-101’).

Quality Assurance / Quality Control

Mineralized intervals reported herein are calculated using an average 0.12% CuEq lower cut-off over contiguous 20-metre intersections (shorter intervals as the case may be at the upper and lower limits of reported intervals). Intervals of 20 metres or less are not reported unless indicating significantly higher grades . True widths are estimated at 90 – 92% of the reported core length intervals.

Osisko Metals adheres to a strict QA/QC program for core handling, sampling, sample transportation and analyses, including insertion of blanks and standards in the sample stream. Drill core is drilled in HQ or NQ diameter and securely transported to its core processing facility on site, where it is logged, cut and sampled. Samples selected for assay are sealed and shipped to ALS Canada Ltd.’s preparation facility in Sudbury. Sample preparation details (code PREP-31DH) are available on the ALS Canada website. Pulps are analyzed at the ALS Canada Ltd. facility in North Vancouver, BC. All samples are analyzed by four acid digestion followed by both ICP-AES and ICP-MS for Cu, Mo and Ag.

Option Grant

The Company announces that, effective August 12, 2025, it has granted to an employee of the Company an aggregate of 125,000 stock options (‘Options’) pursuant to the Osisko Metals omnibus equity incentive plan.

The Options have an exercise price of $0.44 per share and a five-year term from the date of grant, and vest annually in equal thirds beginning on the first anniversary of the date of grant.

About Osisko Metals

Osisko Metals Incorporated is a Canadian exploration and development company creating value in the critical metals sector, with a focus on copper and zinc. The Company acquired a 100% interest in the past-producing Gaspé Copper mine from Glencore Canada Corporation in July 2023. The Gaspé Copper mine is located near Murdochville in Québec s Gaspé Peninsula. The Company is currently focused on resource expansion of the Gaspé Copper system, with current Indicated Mineral Resources of 824 Mt averaging 0.34% CuEq and Inferred Mineral Resources of 670 Mt averaging 0.38% CuEq (in compliance with NI 43-101). For more information, see Osisko Metals’ November 14, 2024 news release entitled ‘Osisko Metals Announces Significant Increase in Mineral Resource at Gaspé Copper’. Gaspé Copper hosts the largest undeveloped copper resource in eastern North America, strategically located near existing infrastructure in the mining-friendly province of Québec.

In addition to the Gaspé Copper project, the Company is working with Appian Capital Advisory LLP through the Pine Point Mining Limited joint venture to advance one of Canada s largest past-producing zinc mining camps, the Pine Point project, located in the Northwest Territories. The current mineral resource estimate for the Pine Point project consists of Indicated Mineral Resources of 49.5 Mt averaging 5.52% ZnEq and Inferred Mineral Resources of 8.3 Mt averaging 5.64% ZnEq (in compliance with NI 43-101). For more information, see Osisko Metals June 25, 2024 news release entitled ‘Osisko Metals releases Pine Point mineral resource estimate: 49.5 million tonnes of indicated resources at 5.52% ZnEq’. The Pine Point project is located on the south shore of Great Slave Lake, NWT, close to infrastructure, with paved road access, an electrical substation and 100 kilometers of viable haul roads.

For further information on this news release, visit www.osiskometals.com or contact:

Don Njegovan, President
Email: info@osiskometals.com
Phone: (416) 500-4129

Cautionary Statement on Forward-Looking Information

This news release contains ‘forward-looking information’ within the meaning of applicable Canadian securities legislation based on expectations, estimates and projections as at the date of this news release. Any statement that involves predictions, expectations, interpretations, beliefs, plans, projections, objectives, assumptions, future events or performance (often, but not always, using phrases such as ‘expects’, or ‘does not expect’, ‘is expected’, ‘interpreted’, ‘management’s view’, ‘anticipates’ or ‘does not anticipate’, ‘plans’, ‘budget’, ‘scheduled’, ‘forecasts’, ‘estimates’, ‘potential’, ‘feasibility’, ‘believes’ or ‘intends’ or variations of such words and phrases or stating that certain actions, events or results ‘may’ or ‘could’, ‘would’, ‘might’ or ‘will’ be taken, occur or be achieved) are not statements of historical fact and may be forward-looking information and are intended to identify forward-looking information. This news release contains forward-looking information pertaining to, among other things: the tax treatment of the FT Units; the timing of incurring the Qualifying Expenditures and the renunciation of the Qualifying Expenditures; the ability to advance Gaspé Copper to a construction decision (if at all); the ability to increase the Company’s trading liquidity and enhance its capital markets presence; the potential re-rating of the Company; the ability for the Company to unlock the full potential of its assets and achieve success; the ability for the Company to create value for its shareholders; the advancement of the Pine Point project; the anticipated resource expansion of the Gaspé Copper system and Gaspé Copper hosting the largest undeveloped copper resource in eastern North America.

Forward-looking information is not a guarantee of future performance and is based upon a number of estimates and assumptions of management, in light of management’s experience and perception of trends, current conditions and expected developments, as well as other factors that management believes to be relevant and reasonable in the circumstances, including, without limitation, assumptions about: the ability of exploration results, including drilling, to accurately predict mineralization; errors in geological modelling; insufficient data; equity and debt capital markets; future spot prices of copper and zinc; the timing and results of exploration and drilling programs; the accuracy of mineral resource estimates; production costs; political and regulatory stability; the receipt of governmental and third party approvals; licenses and permits being received on favourable terms; sustained labour stability; stability in financial and capital markets; availability of mining equipment and positive relations with local communities and groups. Forward-looking information involves risks, uncertainties and other factors that could cause actual events, results, performance, prospects and opportunities to differ materially from those expressed or implied by such forward-looking information. Factors that could cause actual results to differ materially from such forward-looking information are set out in the Company’s public disclosure record on SEDAR+ (www.sedarplus.ca) under Osisko Metals’ issuer profile. Although the Company believes that the assumptions and factors used in preparing the forward-looking information in this news release are reasonable, undue reliance should not be placed on such information, which only applies as of the date of this news release, and no assurance can be given that such events will occur in the disclosed time frames or at all. The Company disclaims any intention or obligation to update or revise any forward-looking information, whether as a result of new information, future events or otherwise, other than as required by law.

Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accept responsibility for the adequacy or accuracy of this news release. No stock exchange, securities commission or other regulatory authority has approved or disapproved the information contained herein.

Photos accompanying this announcement are available at:
https://www.globenewswire.com/NewsRoom/AttachmentNg/f12ebf89-5e37-4f45-86a2-3476365db1e2
https://www.globenewswire.com/NewsRoom/AttachmentNg/2a67e753-d0a2-4e74-8717-d7ee5bf555b7

News Provided by GlobeNewswire via QuoteMedia

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Shiba Inu price trades at $0.0000135 today, August 13, with a 4.42% increase in 24 hours. Amid these gains, the burn rate has exploded by more than 48,000%. The transactions done by whales have also surged by 188%. These developments hint that SHIB might get to $0.0000254. Shiba Inu Price Eyes $0.0000254 Amid Bullish Pattern

The post Shiba Inu Price Forecast as Burn Rate Explodes 48,000% and Whale Transactions Soar – Is $0.0000254 Next? appeared first on CoinGape.

Nasdaq-listed BTCS Inc. has purchased three Pudgy Penguins NFTs to expand its treasury holdings. The move follows the PENGU price’s bullish momentum as corporate NFT treasury talks gain popularity. BTCS Diversifies Treasury With Pudgy Penguins NFT Purchase In fresh treasury actions, BTCS increased its reserves by acquiring three Pudgy Penguins NFTs. This represents a strategic

The post Nasdaq-Listed BTCS Adds Pudgy Penguins NFTs to Treasury, PENGU Price Climbs appeared first on CoinGape.

Kraken:- Since the beginning of this year, the leading crypto exchange Kraken has been witnessing a major reshuffle in its legal team. In a latest instance, its litigation had Michael Ono announced his move from the exchange after 6 years of tenure. In a recent X post, Michael announced that “he is no longer leading

The post After Marco, Another Kraken Lawyer Michael O’Connor Departs From the Exchange appeared first on CoinGape.

Ethereum price is getting closer to an all-time high. It trades at $4,693 today, August 13, with a 9% surge in 24 hours. Amid these gains, the CEO of ARK Invest, Cathie Wood, is doubling down on her bullish bias towards ETH. Analysts are also leaning bullish, saying it might reach $22,000. Analyst Targets $22,000

The post Ethereum Price Nears ATH as Cathie Wood Doubles Down on ETH – Analyst Eyes $22K Rally appeared first on CoinGape.

Elon Musk on Monday threatened Apple with legal action over alleged antitrust violations related to rankings of the Grok AI chatbot app, which is owned by his artificial intelligence startup xAI.

“Apple is behaving in a manner that makes it impossible for any AI company besides OpenAI to reach #1 in the App Store, which is an unequivocal antitrust violation. xAI will take immediate legal action,” Musk wrote in a post on his social media platform X.

Apple declined to comment on Musk’s threat.

“Why do you refuse to put either X or Grok in your ‘Must Have’ section when X is the #1 news app in the world and Grok is #5 among all apps? Are you playing politics?” Musk said in another post.

Apple last year partnered with OpenAI to integrate its ChatGPT chatbot into iPhone, iPad, Mac laptop and desktop products. Musk at the time said: “If Apple integrates OpenAI at the OS level, then Apple devices will be banned at my companies. That is an unacceptable security violation.”

Prior to his legal threats against Apple, Musk had celebrated Grok surpassing Google as the fifth top free app on the App Store. When contacted by CNBC, xAI did not immediately respond to a request for further information on a potential lawsuit.

CNBC confirmed that ChatGPT was ranked No. 1 in the top free apps section of the American iOS store, and was the only AI chatbot in Apple’s “Must-Have Apps” section. The App Store also featured a link to download OpenAI’s new flagship AI model, ChatGPT-5 at the top of its “Apps” section.

OpenAI on Thursday announced GPT-5, its latest and most advanced large-scale AI model, following xAI’s release of its newest chatbot, Grok 4, last month.

Musk has an ongoing feud with ChatGPT maker OpenAI, which he co-founded in 2015. The billionaire stepped down from its board in 2018, four years after saying that AI was “potentially more dangerous than nukes.”

He is now suing the Microsoft-backed startup, and its CEO Sam Altman, alleging they abandoned OpenAI’s founding mission to develop artificial intelligence “for the benefit of humanity broadly.”

Robert Keele, who headed the legal department at xAI, announced last week that he had left the company to spend more time with his family. In his announcement, Keele also acknowledged “daylight between our worldviews,” referring to Musk.

In response to Musk’s antitrust threats against Apple, OpenAI CEO Sam Altman said in an X post: “This is a remarkable claim given what I have heard alleged that Elon does to manipulate X to benefit himself and his own companies and harm his competitors and people he doesn’t like.”

This is not the first time Apple has been challenged on antitrust grounds. In a landmark case, the Department of Justice last year sued the company over charges of running an iPhone ecosystem monopoly.

In June, a panel of judges also denied an emergency application from Apple to halt the changes to its App Store resulting from a ruling that the company could no longer charge a commission on payment links inside its apps, nor tell developers how the links should look.

— CNBC’s Kif Leswing and Lora Kolodny contributed to this article.

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Generative artificial intelligence (AI) has helped a group of scientists identify five new materials that could power the next wave of batteries without relying on lithium.

The study, published on June 26 in Cell Reports Physical Science, focuses on materials that could enable multivalent-ion batteries — a technology long touted for its potential, but hindered by practical challenges.

The lithium problem for batteries

Lithium dominates in batteries used in everything from smartphones to electric vehicles, but faces challenges — it is costly to extract, geographically concentrated and comes with environmental and geopolitical concerns.

As global demand for batteries surges, researchers are racing to find viable alternatives that are both abundant and efficient. Multivalent-ion batteries offer one potential path forward. Unlike lithium-ion batteries, which carry a single positive charge, multivalent-ion batteries using materials like magnesium or zinc carry two or three.

In theory, this means that they can pack more energy into the same space. However, their larger size and stronger charge make it difficult for them to move through standard battery materials.

“One of the biggest hurdles wasn’t a lack of promising battery chemistries — it was the sheer impossibility of testing millions of material combinations,” said lead author Dibakar Datta, a professor of mechanical and industrial engineering at the New Jersey Institute of Technology. “We turned to generative AI as a fast, systematic way to sift through that vast landscape and spot the few structures that could truly make multivalent batteries practical.”

To tackle the challenge, Datta’s team developed a “dual AI” system. The first part, a crystal diffusion variational autoencoder (CDVAE), was trained on vast datasets of known crystal structures. It could generate entirely new porous transition metal oxides, a class of material known for its structural flexibility and ionic conductivity.

The second part was a fine-tuned large language model (LLM) designed to narrow the list.

It focused on materials closest to thermodynamic stability, a critical factor in determining whether a compound can realistically be made and used in the real world.

The CDVAE cast a wide net, creating thousands of hypothetical structures with large, open channels. The LLM then acted as a filter, selecting only those most likely to hold up under actual manufacturing and operational conditions.

Five new battery candidates

“Our AI tools dramatically accelerated the discovery process, which uncovered five entirely new porous transition metal oxide structures that show remarkable promise,” Datta said.

These structures, the study suggests, offer unusually large pathways for ion movement, a crucial step toward making multivalent batteries that charge quickly and last for long periods of time. Quantum mechanical simulations and stability tests confirmed that the materials should be both synthetically feasible and structurally sound.

The five compounds now move to the next stage — experimental synthesis in collaboration with partner laboratories. If successful, they could be incorporated into prototype batteries and eventually scaled for commercial production.

Traditional materials research is often a painstaking, years-long process of hypothesis, synthesis and testing.

By contrast, AI can rapidly explore enormous “material spaces” that would be impossible for humans to search manually, flagging only the most promising candidates for further investigation.

What it means for the batteries of tomorrow

Multivalent-ion batteries have been studied for decades, yet few have reached commercial readiness because the necessary materials either didn’t conduct ions well enough or degraded too quickly.

By using AI to overcome that bottleneck, the research team hopes to accelerate not just battery chemistry, but also the infrastructure needed to support electrification on a global scale.

However, the five materials identified by Datta’s team aren’t ready to replace lithium tomorrow. They still need to be synthesized, tested in lab-scale batteries and proven to perform under real-world conditions.

Safety, scalability and cost effectiveness all remain open questions.

Still, the study’s authors argue that their AI framework has already proven its value by shrinking what could have been a decades-long search into a matter of months.

“This is more than just discovering new battery materials — it’s about establishing a rapid, scalable method to explore any advanced materials, from electronics to clean energy solutions, without extensive trial and error,” Datta added.

Securities Disclosure: I, Giann Liguid, hold no direct investment interest in any company mentioned in this article.

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Lithium, a naturally occurring trace element in the brain, may be able to unlock a key medical mystery: why some people develop Alzheimer’s disease and others don’t, despite similar brain changes.

In a recently published study, scientists at Harvard Medical School state that lithium not only exists in the human brain at biologically meaningful levels, but also appears to protect against neurodegeneration.

Additionally, their work shows that lithium supports the function of all major brain cell types.

The decade-long study drew on mouse experiments and analyses of human brain and blood samples across the spectrum of cognitive health. The Harvard team discovered that as amyloid beta, the sticky protein associated with Alzheimer’s, begins to accumulate, it binds to lithium and depletes its availability in the brain. This drop in lithium impairs neurons, glial cells and other brain structures, accelerating memory loss and disease progression.

“The idea that lithium deficiency could be a cause of Alzheimer’s disease is new and suggests a different therapeutic approach,” said Bruce Yankner, who is the senior author of the study.

Yankner, a professor of genetics and neurology at Harvard Medical School who in the 1990s was the first to show that amyloid beta is toxic to nerve cells, said the new findings open the door to treatments that address the disease in its entirety, rather than targeting single features like amyloid plaques or tau tangles.

To explore this possibility, researchers screened for lithium compounds that could evade capture by amyloid beta.

They identified lithium orotate as the most promising candidate. In mice, the compound reversed Alzheimer’s-like brain changes, prevented cell damage and restored memory, even in animals with advanced disease.

Crucially, the effective dose was about one-thousandth of that used in psychiatric treatments, avoiding the toxicity risk that has hampered lithium’s clinical use in older patients.

“You have to be careful about extrapolating from mouse models, and you never know until you try it in a controlled human clinical trial,” Yankner cautioned. “But so far the results are very encouraging.”

The path to these findings began with access to an unusually rich source of brain tissue.

Working with the Rush Memory and Aging Project in Chicago, the team examined postmortem samples from thousands of donors, from cognitively healthy individuals to those with mild cognitive impairment and full-blown Alzheimer’s.

Using advanced mass spectrometry, they measured trace levels of about 30 metals. Lithium stood out as the only one whose levels dropped sharply at the earliest stages of memory loss.

The pattern matched earlier population studies linking higher environmental lithium levels, including in drinking water, to lower dementia rates. But unlike those correlations, the Harvard team directly measured brain lithium and established a normal range for healthy individuals who had never taken lithium as medication.

“Lithium turns out to be like other nutrients we get from the environment, such as iron and vitamin C,” Yankner said. “It’s the first time anyone’s shown that lithium exists at a natural level that’s biologically meaningful without giving it as a drug.”

To test whether this deficiency was more than an association, the researchers fed healthy mice a lithium-restricted diet, lowering brain lithium to levels seen in Alzheimer’s patients.

The animals developed brain inflammation, lost connections between neurons and showed cognitive decline; however, replenishing them with lithium orotate reversed these changes. What’s more, mice given the compound from early adulthood were protected from developing Alzheimer’s-like symptoms altogether.

The findings raise several possibilities. Measuring lithium levels in blood could become a tool for early screening, identifying people at risk before symptoms emerge. Furthermore, amyloid-evading lithium compounds could be tested as preventive or therapeutic agents, potentially altering the disease course more fundamentally than existing drugs.

For now, researchers stress that no one should self-medicate with lithium supplements.

The team emphasized that the safety and efficacy of lithium orotate in humans remain unproven, and clinical trials will be needed to determine whether the dramatic benefits seen in mice translate to people.

Securities Disclosure: I, Giann Liguid, hold no direct investment interest in any company mentioned in this article.

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Here’s a quick recap of the crypto landscape for Monday (August 11) as of 9:00 p.m. UTC.

Get the latest insights on Bitcoin, Ethereum and altcoins, along with a round-up of key cryptocurrency market news.

Bitcoin and Ethereum price update

Bitcoin (BTC) was priced at US$118,815, down by 0.1 percent over the last 24 hours and its lowest valuation on Monday. Its highest price for the day was US$120,693.

Bitcoin price performance, August 11, 2025.

Chart via TradingView.

Analyst Omkar Godbole offered a cautious outlook, pointing to lower trading volumes for Bitcoin despite similar prices in July and a Coinbase Global (NASDAQ:COIN) discount suggesting weak US institutional demand.

Ethereum (ETH) has outperformed after a weekend rally.

Ethereum broke past US$4,300 on Monday as FG Nexus announced the acquisition of 47,331 ETH, worth about US$200 million. Meanwhile, data from Etherscan shows rising daily transaction counts over the past several weeks.

Creator coins like ZRO and PUMP also saw gains after announcements like Coinbase’s new DEX feature and LayerZero’s acquisition. Bondex CEO Ignacio Palomera called these developments an evolution in how creators can monetize their content. US consumer price index data on Tuesday (August 12) could fuel or dampen the crypto rally.

Altcoin price update

  • Solana (SOL) was priced at US$176.39, down by 3.6 percent over 24 hours and its lowest valuation for the day. Its highest price was US$180.86.
  • XRP was trading for US$3.16, down 1.7 percent in the past 24 hours and at its lowest valuation of the day. Its highest was US$3.22.
  • Sui (SUI) was trading at US$3.69, down by 5 percent over the past 24 hours, and its lowest valuation of the day. Its highest level was US$3.77.
  • Cardano (ADA) was trading at US$0.783, down by 3 percent over 24 hours and its lowest valuation on Monday. Its highest was US$0.8008.

Today’s crypto news to know

Bullish aims for US$4.82 billion valuation in upsized IPO

Bullish has increased the size of its planned initial public offering (IPO), targeting a valuation of up to US$4.82 billion. It plans to raise as much as US$990 million by selling 30 million shares priced between US$32 and US$33 each, a higher range than its previous filing, but still below its US$9 billion target in a failed 2021 SPAC merger.

The cryptocurrency exchange said it will convert a significant portion of its IPO proceeds into US-dollar-backed stablecoins through partnerships with token issuers. BlackRock-managed funds and Cathie Wood’s ARK Investment have shown interest in purchasing up to US$200 million worth of shares.

Bullish is expected to price the offering on Tuesday and debut on the NYSE under the ticker “FLY” the next day.

Tether and Rumble propose joint acquisition of Northern Data

Tether and Rumble (NASDAQ:RUM) have proposed to jointly acquire all shares of artificial intelligence infrastructure company Northern Data, according to a press release issued on Monday.

According to the proposed terms, USDt issuer Tether, already Northern Data’s largest shareholder, would support the transaction, which would see each Northern Data shareholder receive 2.319 newly issued Class A Rumble shares for each Northern Data share offered, leading to roughly 33.3 percent of Rumble ownership being transferred to Northern Data shareholders. The final exchange ratio may be adjusted for the potential sale of Peak Mining and a related debt reduction, which would increase the exchange ratio.

Subject to definitive documentation, Tether would also significantly increase its investment in Rumble, becoming a key customer with a multi-year GPU purchase commitment.

Chainlink to partner with ICE

Blockchain oracle platform Chainlink announced a partnership with US-based Fortune 500 company Intercontinental Exchange (NYSE:ICE) on Monday to bring foreign exchange and precious metals data onchain.

The collaboration will unite Intercontinental’s consolidated feed, an aggregator of market data from over 300 global exchanges and marketplaces, with Chainlink Data Streams’ derived data sets, which provide market information to power tokenization for over 2,000 decentralized applications and major financial institutions.

This partnership is the latest move to further integrate traditional market infrastructure with blockchain systems.

El Salvador targets wealthy investors with new Bitcoin banking law

El Salvador has approved a new investment banking law designed to attract institutional and high-net-worth crypto investors. Licensed investment banks with at least US$50 million in capital will be able to provide Bitcoin and other digital asset services, but only to clients meeting “sophisticated investor” criteria.

Requirements include at least US$250,000 in liquid assets and advanced financial knowledge.

The banks will be allowed to issue bonds, structure public-private projects and offer digital asset products. Lawmakers say the changes aim to position the country as a regional financial hub and draw in foreign private capital.

The move comes as President Nayib Bukele consolidates political power through constitutional reforms extending presidential terms and removing term limits.

Blue Origin to accept crypto payments for space flights

According to a Monday press release, Jeff Bezos’ Blue Origin has partnered with payment processing company Shift4 Payments (NYSE:FOUR) to allow customers to buy tickets to outer space using crypto and stablecoins.

Trips will take place on Blue Origin’s New Shepard reusable rockets, and direct payments will now be accepted from popular wallets from the likes of MetaMask and Coinbase.

“Our mission has always been to revolutionize commerce by simplifying the transaction process, and we’re thrilled to now extend that vision beyond Earth,” said Taylor Lauber, CEO of Shift4.

“This partnership will enable adventurous travelers to book the adventure of a lifetime, no matter their preferred payment method — all with a simple, frictionless experience,’ he added. Blue Origin has flown more than 75 passengers past the Kármán Line, the boundary separating Earth’s atmosphere and space.

“We believe crypto and stablecoins are going to become an increasingly popular way for consumers to pay, particularly for high-end purchases, as both the consumer and merchant benefit financially from these transactions,” commented Alex Wilson, head of crypto at Shift4.

Securities Disclosure: I, Giann Liguid, hold no direct investment interest in any company mentioned in this article.

Securities Disclosure: I, Meagen Seatter, hold no direct investment interest in any company mentioned in this article.

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